ABO blood group predictions are brand new, and still under development. We're rolling it out to you so we can see how it performs on real data. All conclusions are still greatly limited by the general lack of phased data, the lack of genotyping at all of the necessary snps, and other factors.
best guess:ABO blood type probA
rs8176719(I;D) rs8176746(C;C)rs8176719(I;D) indicates you have one type-O allele
rs8176746(C;C) and no genotype for rs8176747, reasonable to assume type-A
you were not genotyped at either rs590787 nor i4001527 so it is impossible to see your Rh blood type
But the ABO system is quite limited
Blood, you see, doesn't just come in types A, B, AB, and O. The "positive" or "negative?" Nope. In fact, let's get all the way into the weeds: Scientists have since discovered over 300 proteins that contribute to blood type. The AB+ on your blood donor card? Yeah, that's a massive oversimplification... read more at Beyond Blood Type: Genomics Can Show What You're Really Made Of
or
It would be straightforward if we all had the same blood. But we don't. On the surface of every one of our red blood cells, we have up to 342 antigens - molecules capable of triggering the production of specialised proteins called antibodies. It is the presence or absence of particular antigens that determines someone's blood type.
Some 160 of the 342 blood group antigens are 'high-prevalence', which means that they are found on the red blood cells of most people. If you lack an antigen that 99 per cent of people in the world are positive for, then your blood is considered rare. If you lack one that 99.99 per cent of people are positive for, then you have very rare blood.
If a particular high-prevalence antigen is missing from your red blood cells, then you are 'negative' for that blood group. If you receive blood from a 'positive' donor, then your own antibodies may react with the incompatible donor blood cells, triggering a further response from the immune system. These transfusion reactions can be lethal. Read more at The man with the golden blood.
Known ABO SNPs
Index | Gene | SNP | Geno | Repute | Magnitude | Summary |
---|---|---|---|---|---|---|
1 | rs7466519 | not tested | ||||
2 | rs8176750 | not tested | ||||
3 | rs56202119 | not tested | ||||
4 | i4000505 | not tested | ||||
5 | rs56231718 | not tested | ||||
6 | rs55788852 | not tested | ||||
7 | rs55927860 | not tested | ||||
8 | ABO | rs8176749 | (G;G) | 0.0 | ||
9 | rs56190619 | not tested | ||||
10 | rs55783488 | not tested | ||||
11 | rs56355240 | not tested | ||||
12 | i4000504 | not tested | ||||
13 | rs56409303 | not tested | ||||
14 | rs55805279 | not tested | ||||
15 | rs56106480 | not tested | ||||
16 | rs8176747 | not tested | ||||
17 | rs41302905 | not tested | ||||
18 | ABO | rs8176746 | (C;C) | 0.0 | ||
19 | rs8176745 | not tested | ||||
20 | rs55951833 | not tested | ||||
21 | rs8176743 | not tested | ||||
22 | i5007173 | not tested | ||||
23 | rs55739900 | not tested | ||||
24 | rs56116432 | not tested | ||||
25 | rs56031507 | not tested | ||||
26 | ABO | rs8176741 | (G;G) | |||
27 | rs56408700 | not tested | ||||
28 | ABO | rs8176740 | (T;T) | 0.0 | ||
29 | rs55827808 | not tested | ||||
30 | rs8176739 | not tested | ||||
31 | rs56223957 | not tested | ||||
32 | rs56189011 | not tested | ||||
33 | rs56089890 | not tested | ||||
34 | rs55727303 | not tested | ||||
35 | rs7853989 | not tested | ||||
36 | ABO | rs55964869 | (C;C) | Good | 0.0 | common in complete genomics |
37 | rs55756402 | not tested | ||||
38 | i5007171 | not tested | ||||
39 | ABO | rs1053878 | (C;T) | |||
40 | rs55658842 | not tested | ||||
41 | rs7873522 | not tested | ||||
42 | rs8176732 | not tested | ||||
43 | ABO | rs2073824 | (A;A) | |||
44 | ABO | rs8176722 | (C;C) | |||
45 | rs8176721 | not tested | ||||
46 | ABO | rs8176720 | (A;A) | |||
47 | ABO | rs8176719 | (I;D) | |||
48 | rs56231711 | not tested | ||||
49 | rs8176717 | not tested | ||||
50 | ABO | rs512770 | (G;G) | |||
51 | rs641959 | not tested | ||||
52 | rs514708 | not tested | ||||
53 | rs55958637 | not tested | ||||
54 | rs549446 | not tested | ||||
55 | ABO | rs8176704 | (A;G) | |||
56 | rs574347 | not tested | ||||
57 | rs688976 | not tested | ||||
58 | ABO | rs687289 | (A;G) | |||
59 | rs2073828 | not tested | ||||
60 | rs55876802 | not tested | ||||
61 | ABO | rs8176694 | (A;A) | |||
62 | rs672316 | not tested | ||||
63 | ABO | rs657152 | (A;C) | |||
64 | rs8176682 | not tested | ||||
65 | rs474279 | not tested | ||||
66 | rs500498 | not tested | ||||
67 | rs505922 | not tested | ||||
68 | rs507666 | not tested | ||||
69 | ABO | rs630014 | (C;C) |
Index | Gene | SNP | Geno | Repute | Magnitude | Summary |
---|---|---|---|---|---|---|
1 | ABO | rs1053878 | (C;T) | |||
2 | ABO | rs2073824 | (A;A) | |||
3 | rs2073828 | not tested | ||||
4 | rs2519093 | not tested | ||||
5 | rs41302905 | not tested | ||||
6 | rs500498 | not tested | ||||
7 | rs505922 | not tested | ||||
8 | rs507666 | not tested | ||||
9 | ABO | rs512770 | (G;G) | |||
10 | rs514659 | not tested | ||||
11 | ABO | rs55722397 | (C;C) | Good | 0.0 | common in complete genomics |
12 | ABO | rs55964869 | (C;C) | Good | 0.0 | common in complete genomics |
13 | rs56392308 | not tested | ||||
14 | rs574347 | not tested | ||||
15 | rs612169 | not tested | ||||
16 | ABO | rs630014 | (C;C) | |||
17 | rs643434 | not tested | ||||
18 | rs644234 | not tested | ||||
19 | ABO | rs657152 | (A;C) | |||
20 | ABO | rs687289 | (A;G) | |||
21 | ABO | rs687621 | (A;G) | |||
22 | rs7853989 | not tested | ||||
23 | ABO | rs8176694 | (A;A) | |||
24 | ABO | rs8176704 | (A;G) | |||
25 | ABO | rs8176719 | (I;D) | |||
26 | ABO | rs8176720 | (A;A) | |||
27 | ABO | rs8176722 | (C;C) | |||
28 | ABO | rs8176740 | (T;T) | 0.0 | ||
29 | ABO | rs8176741 | (G;G) | |||
30 | rs8176743 | not tested | ||||
31 | ABO | rs8176746 | (C;C) | 0.0 | ||
32 | rs8176747 | not tested | ||||
33 | ABO | rs8176749 | (G;G) | 0.0 | ||
34 | rs8176750 | not tested |
Index | Gene | SNP | Geno | Repute | Magnitude | Summary |
---|---|---|---|---|---|---|
1 | ABCG2 | rs2231142 | (A;C) | Bad | 2.1 | 1.74x increased gout risk; gefinitib takers 4x more susceptible to diarrhea |
2 | ABCG2 | rs72552713 | (G;G) | Good | 0.0 | common in complete genomics |
3 | ANKK1 | rs1800497 | (C;T) | Bad | 2.9 | A1/A2: Bad at avoidance of errors. 0.5x lower OCD risk, 0.87x lower Tardive Diskinesia risk, higher ADHD risk. More Alcohol Dependence. Lower risk of Postoperative Nausea. Increased obesity. Bupropion... |
4 | APOE | rs429358 | (T;T) | Good | 0.0 | common |
5 | rs7412 | not tested | ||||
6 | COMT | rs4680 | (A;A) | Good | 2.5 | (worrier) advantage in memory and attention tasks |
7 | CYP1A2 | rs12720461 | (C;C) | Good | 0.0 | normal |
8 | rs2069514 | not tested | ||||
9 | rs35694136 | not tested | ||||
10 | rs56107638 | not tested | ||||
11 | CYP1A2 | rs762551 | (A;C) | 2.1 | Carrier of one CYP1A2*1F allele; Slow Caffeine Metabolizer. | |
12 | CYP2B6 | rs12721655 | (A;A) | Good | 0.0 | common on affy axiom data |
13 | rs2279343 | not tested | ||||
14 | CYP2B6 | rs28399499 | (T;T) | Good | 0.0 | common in complete genomics |
15 | rs3211371 | not tested | ||||
16 | rs34097093 | not tested | ||||
17 | CYP2B6 | rs34223104 | (T;T) | Good | 0.0 | common in complete genomics |
18 | CYP2B6 | rs35303484 | (A;A) | Good | 0.0 | common/normal |
19 | CYP2B6 | rs3745274 | (T;T) | Bad | 2.0 | |
20 | rs12248560 | not tested | ||||
21 | rs17878459 | not tested | ||||
22 | rs17884712 | not tested | ||||
23 | rs17885098 | not tested | ||||
24 | rs17886522 | not tested | ||||
25 | CYP2C19 | rs28399504 | (A;A) | Good | 0.0 | normal |
26 | rs3758580 | not tested | ||||
27 | CYP2C19 | rs41291556 | (T;T) | Good | 0.0 | normal |
28 | CYP2C19 | rs4244285 | (G;G) | Good | 0.0 | normal |
29 | CYP2C19 | rs4986893 | (G;G) | Good | 0.0 | normal |
30 | CYP2C19 | rs55640102 | (A;A) | Good | 0.0 | normal |
31 | CYP2C19 | rs56337013 | (C;C) | Good | 0.0 | normal |
32 | rs6413438 | not tested | ||||
33 | rs72552267 | not tested | ||||
34 | CYP2C19 | rs72558186 | (T;T) | Good | 0.0 | normal |
35 | CYP2C9 | rs1057910 | (A;C) | Bad | 2.5 | CYP2C9*3 carrier; average 40% reduction in warfarin metabolism |
36 | rs1799853 | not tested | ||||
37 | rs28371685 | not tested | ||||
38 | CYP2C9 | rs28371686 | (C;C) | Good | 0.0 | normal |
39 | rs56165452 | not tested | ||||
40 | CYP2C9 | rs72558187 | (T;T) | Good | 0.0 | normal |
41 | CYP2C9 | rs72558188 | (I;I) | Good | 0.0 | normal |
42 | rs72558190 | not tested | ||||
43 | rs7900194 | not tested | ||||
44 | rs7900194 | not tested | ||||
45 | CYP2C9 | rs9332130 | (A;A) | Good | 0.0 | normal |
46 | CYP2C9 | rs9332131 | (I;I) | Good | 0.0 | normal |
47 | CYP2C9 | rs9332239 | (C;C) | Good | 0.0 | normal |
48 | rs1065852 | not tested | ||||
49 | CYP2D6 | rs1080985 | (C;C) | 0.1 | a common variant | |
50 | rs147960066 | not tested | ||||
51 | CYP2D6 | rs16947 | (A;G) | 0.1 | a common variant | |
52 | CYP2D6 | rs28371706 | (C;C) | Good | 0.0 | normal |
53 | CYP2D6 | rs28371720 | (I;I) | |||
54 | rs28371725 | not tested | ||||
55 | rs35742686 | not tested | ||||
56 | rs3892097 | not tested | ||||
57 | CYP2D6 | rs5030655 | (I;I) | Good | 0.0 | normal |
58 | CYP2D6 | rs5030862 | (G;G) | Good | 0.0 | normal |
59 | rs5030863 | not tested | ||||
60 | rs5030865 | not tested | ||||
61 | rs5030865 | not tested | ||||
62 | rs5030867 | not tested | ||||
63 | rs59421388 | not tested | ||||
64 | CYP2D6 | rs72549349 | (C;C) | Good | 0.0 | common in complete genomics |
65 | CYP2D6 | rs72549351 | (I;I) | |||
66 | rs72549353 | not tested | ||||
67 | CYP2D6 | rs72549354 | (D;D) | |||
68 | rs72549357 | not tested | ||||
69 | rs769258 | not tested | ||||
70 | CYP3A4 | rs12721629 | (C;C) | Good | 0.0 | normal |
71 | CYP3A | rs2740574 | (A;G) | carrier of one CYP3A4*1B allele | ||
72 | CYP3A4 | rs35599367 | (C;C) | Good | 0.0 | common in complete genomics |
73 | CYP3A4 | rs4646438 | (D;D) | |||
74 | rs4986910 | not tested | ||||
75 | rs4987161 | not tested | ||||
76 | CYP3A4 | rs55785340 | (A;A) | Good | 0.0 | normal |
77 | CYP3A5 | rs10264272 | (C;C) | Good | 0.0 | normal |
78 | rs15524 | not tested | ||||
79 | CYP3A5 | rs28365083 | (C;C) | Good | 0.0 | normal |
80 | rs28383468 | not tested | ||||
81 | rs28383479 | not tested | ||||
82 | rs41279854 | not tested | ||||
83 | CYP3A5 | rs41303343 | (D;D) | |||
84 | CYP3A5 | rs55817950 | (G;G) | Good | 0.0 | normal |
85 | rs55965422 | not tested | ||||
86 | CYP3A5 | rs776746 | (A;G) | 2.0 | carrier of 1 nonfunctional CYP3A5 allele; drug metabolism affects | |
87 | F2 | rs1799963 | (G;G) | Good | 0.0 | normal/common |
88 | F5 | rs6025 | (G;G) | Good | 0.0 | normal/common |
89 | MTHFR | rs1801131 | (A;A) | Good | 0.0 | |
90 | MTHFR | rs1801133 | (C;T) | Bad | 2.5 | 1 copy of C677T allele of MTHFR = 60% efficiency in processing folic acid = could have somewhat elevated homocysteine and low B12 and folate levels |
91 | OPRM1 | rs1799971 | (A;A) | Good | 0.0 | normal |
92 | SLCO1B1 | rs2306283 | (C;T) | |||
93 | SLCO1B1 | rs4149056 | (C;T) | Bad | 2.1 | reduced breakdown of some drugs; 5x increased myopathy risk for statin users |
94 | rs55737008 | not tested | ||||
95 | SLCO1B1 | rs56061388 | (T;T) | |||
96 | rs56101265 | not tested | ||||
97 | rs59502379 | not tested | ||||
98 | SLCO1B1 | rs72559745 | (A;A) | Good | 0.0 | common/normal |
99 | rs1902023 | not tested | ||||
100 | VKORC1 | rs8050894 | (C;G) | average warfarin response (~5 mg/day) | ||
101 | rs9923231 | not tested | ||||
102 | VKORC1 | rs9934438 | (A;G) |